A clinical trial of blood and crystalloid cardioplegia
Autor: | Peter R. McLaughlin, Ronald J. Baird, Donald A.G. Mickle, Stephen E. Fremes, Reginald S. Harding, Susan J. Seawright, George T. Christakis, M. Mindy Madonik, Richard D. Weisel, JoanI vanov, Sylvain Houle |
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Rok vydání: | 1984 |
Předmět: |
Pulmonary and Respiratory Medicine
biology Bypass grafting business.industry Incidence (epidemiology) Ischemia Perioperative medicine.disease Clinical trial Anesthesia biology.protein Medicine Surgery Creatine kinase Myocardial infarction Blood cardioplegia Cardiology and Cardiovascular Medicine business |
Zdroj: | The Journal of Thoracic and Cardiovascular Surgery. 88:726-741 |
ISSN: | 0022-5223 |
DOI: | 10.1016/s0022-5223(19)35440-6 |
Popis: | Although experimental studies suggest that blood cardioplegia provides better protection than crystalloid cardioplegia, clinical studies have been inconclusive. Ninety patients undergoing coronary bypass grafting were randomized to receive either blood (n = 43) or crystalloid cardioplegia (n = 47). The incidence of perioperative myocardial infarction was lower with blood cardioplegia (blood, n = 0; crystalloid, n = 5; p = 0.06), and the maximum MB isoenzyme of creatine kinase was significantly less with blood cardioplegia (blood, 26.3 ± 12.6 U/L; crystalloid, 35.6 ± 17.0 U/L, mean ± standard deviation; p |
Databáze: | OpenAIRE |
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