Level of resistance to antibiotics in plankton and biofilm cultures of Pseudomonas aeruginosa clinical strains
Autor: | V. Yu. Ulyanov, I. V. Babushkina, Е. V. Gladkova, S. P. Shpinyak, I. А. Mamonova |
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Rok vydání: | 2021 |
Předmět: |
medicine.drug_class
Chemistry Pseudomonas aeruginosa Antibiotics Cephalosporin Biofilm biochemical phenomena metabolism and nutrition Plankton bacterial infections and mycoses medicine.disease_cause General Biochemistry Genetics and Molecular Biology Microbiology Antibiotic resistance Amikacin polycyclic compounds medicine medicine.drug |
Zdroj: | Bulletin of Experimental Biology and Medicine. 172:182-185 |
ISSN: | 2413-1008 0365-9615 |
DOI: | 10.47056/0365-9615-2021-172-8-182-185 |
Popis: | Biofilms formed by Pseudomonas aeruginosa strains isolated from biomaterial of patients with implant-associated infection are characterized by much higher resistance to antibiotics of various classes than plankton cultures of these strains. The concentrations of antibiotics causing the death of 90% of P. aeruginosa biofilm (MIC90) was 2-6 μg/ml for fluoroquinolones, 267-356 μg/ml for cephalosporins, and 92-215 μg/ml for amikacin, which significantly (p |
Databáze: | OpenAIRE |
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