Level of resistance to antibiotics in plankton and biofilm cultures of Pseudomonas aeruginosa clinical strains

Autor: V. Yu. Ulyanov, I. V. Babushkina, Е. V. Gladkova, S. P. Shpinyak, I. А. Mamonova
Rok vydání: 2021
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 172:182-185
ISSN: 2413-1008
0365-9615
DOI: 10.47056/0365-9615-2021-172-8-182-185
Popis: Biofilms formed by Pseudomonas aeruginosa strains isolated from biomaterial of patients with implant-associated infection are characterized by much higher resistance to antibiotics of various classes than plankton cultures of these strains. The concentrations of antibiotics causing the death of 90% of P. aeruginosa biofilm (MIC90) was 2-6 μg/ml for fluoroquinolones, 267-356 μg/ml for cephalosporins, and 92-215 μg/ml for amikacin, which significantly (p
Databáze: OpenAIRE