Identification of Virulence Factors Involved in a Murine Model of Severe Achromobacter xylosoxidans Infection
Autor: | Brandon M. Wills, Preeti Garai, Molly O. Riegert, Felix T. Sanchez, Adam M. Pickrum, Dara W. Frank, Kenneth L. Brockman |
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Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Infection and Immunity. |
ISSN: | 1098-5522 0019-9567 |
DOI: | 10.1128/iai.00037-23 |
Popis: | Achromobacter xylosoxidans (Ax) is an opportunistic pathogen and causative agent of numerous infections particularly in immunocompromised individuals with increasing prevalence in cystic fibrosis (CF). To date, investigations have focused on the clinical epidemiology and genomic comparisons of Ax isolates, yet little is known about disease pathology or the role that specific virulence factors play in tissue invasion or damage. |
Databáze: | OpenAIRE |
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