Identification of Virulence Factors Involved in a Murine Model of Severe Achromobacter xylosoxidans Infection

Autor: Brandon M. Wills, Preeti Garai, Molly O. Riegert, Felix T. Sanchez, Adam M. Pickrum, Dara W. Frank, Kenneth L. Brockman
Rok vydání: 2023
Předmět:
Zdroj: Infection and Immunity.
ISSN: 1098-5522
0019-9567
DOI: 10.1128/iai.00037-23
Popis: Achromobacter xylosoxidans (Ax) is an opportunistic pathogen and causative agent of numerous infections particularly in immunocompromised individuals with increasing prevalence in cystic fibrosis (CF). To date, investigations have focused on the clinical epidemiology and genomic comparisons of Ax isolates, yet little is known about disease pathology or the role that specific virulence factors play in tissue invasion or damage.
Databáze: OpenAIRE