Trichostatin A (TSA) levels in response to treatment of rainbow trout with gamma-irradiated trophonts against Ichthyophthirius multifiliis

Autor: Sakineh Yeganeh, Saeed Moodi, Marzieh Heidarieh, Omid Safari
Rok vydání: 2019
Předmět:
Zdroj: Comparative Clinical Pathology. 28:571-574
ISSN: 1618-565X
1618-5641
DOI: 10.1007/s00580-019-02903-4
Popis: Ichthyophthirius multifiliis is a large ciliated protozoan parasite that is widely distributed in freshwater fish. Histone deacetylase inhibitors (HDACi), e.g., trichostatin A (TSA), are recognized as new agents for the treatment of a wide range of parasitic diseases. In this study, TSA levels induced by gamma-irradiated trophonts and alginate/calcium phosphate nanoparticles were measured after 30 days following treatment against I. multifiliis in spleen, kidney, and liver tissues of rainbow trout. This sounds like TSA is an anti-parasitic enzyme that can increase in spleen, kidney, and liver tissues following treatment of rainbow trout against I. multifiliis (P
Databáze: OpenAIRE
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