Trichostatin A (TSA) levels in response to treatment of rainbow trout with gamma-irradiated trophonts against Ichthyophthirius multifiliis
| Autor: | Sakineh Yeganeh, Saeed Moodi, Marzieh Heidarieh, Omid Safari |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Kidney Hematology Ichthyophthirius multifiliis biology urogenital system 040301 veterinary sciences organic chemicals Spleen 04 agricultural and veterinary sciences biology.organism_classification Pathology and Forensic Medicine 0403 veterinary science Andrology Trichostatin A medicine.anatomical_structure Internal medicine medicine Parasite hosting Rainbow trout Histone deacetylase Anatomy medicine.drug |
| Zdroj: | Comparative Clinical Pathology. 28:571-574 |
| ISSN: | 1618-565X 1618-5641 |
| DOI: | 10.1007/s00580-019-02903-4 |
| Popis: | Ichthyophthirius multifiliis is a large ciliated protozoan parasite that is widely distributed in freshwater fish. Histone deacetylase inhibitors (HDACi), e.g., trichostatin A (TSA), are recognized as new agents for the treatment of a wide range of parasitic diseases. In this study, TSA levels induced by gamma-irradiated trophonts and alginate/calcium phosphate nanoparticles were measured after 30 days following treatment against I. multifiliis in spleen, kidney, and liver tissues of rainbow trout. This sounds like TSA is an anti-parasitic enzyme that can increase in spleen, kidney, and liver tissues following treatment of rainbow trout against I. multifiliis (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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