A novel autocrine serotonin receptor in enterochromaffin cells

Autor: Dorne R. Yager, Roberto C. Iglesias, Jarrod D. Day, John M. Kellum
Rok vydání: 2006
Předmět:
Zdroj: Journal of the American College of Surgeons. 203:S19
ISSN: 1072-7515
DOI: 10.1016/j.jamcollsurg.2006.05.045
Popis: INTRODUCTION: The exclusive neuronal location of the 5-HT3 receptor has recently been challenged by studies indicating it is expressed at the enteric mucosal layer. There is also evidence that the 5-HT4 receptor may be an inhibitory receptor. These studies have all been done in intact tissue models. The BON cell is a unique human pancreatic tumor cell line with enterochromaffin (EC) cell characteristics. The aim of this study was to identify autocrine receptors on BON cells.
Databáze: OpenAIRE