A novel autocrine serotonin receptor in enterochromaffin cells
Autor: | Dorne R. Yager, Roberto C. Iglesias, Jarrod D. Day, John M. Kellum |
---|---|
Rok vydání: | 2006 |
Předmět: | |
Zdroj: | Journal of the American College of Surgeons. 203:S19 |
ISSN: | 1072-7515 |
DOI: | 10.1016/j.jamcollsurg.2006.05.045 |
Popis: | INTRODUCTION: The exclusive neuronal location of the 5-HT3 receptor has recently been challenged by studies indicating it is expressed at the enteric mucosal layer. There is also evidence that the 5-HT4 receptor may be an inhibitory receptor. These studies have all been done in intact tissue models. The BON cell is a unique human pancreatic tumor cell line with enterochromaffin (EC) cell characteristics. The aim of this study was to identify autocrine receptors on BON cells. |
Databáze: | OpenAIRE |
Externí odkaz: |