Induction of malate dehydrogenase and acetylcholinesterase by 20-hydroxyecdysone and heat shock in Drosophila ovaries
| Autor: | G.N. Goulielmos, S.N. Alahiotis |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
chemistry.chemical_classification
biology medicine.medical_treatment 20-Hydroxyecdysone biology.organism_classification Biochemistry Acetylcholinesterase Malate dehydrogenase chemistry.chemical_compound Steroid hormone Enzyme chemistry Insect Science Heat shock protein Drosophilidae Shock (circulatory) medicine medicine.symptom Molecular Biology |
| Zdroj: | Insect Biochemistry. 19:393-399 |
| ISSN: | 0020-1790 |
| DOI: | 10.1016/0020-1790(89)90044-9 |
| Popis: | The molting hormone 20-hydroxyecdysone induces de novo synthesis of cytoplasmic malate dehydrogenase (cMDH) in Drosophila ovaries, but not mitochondrial MDH (mMDH). A second enzyme, acetylcholinesterase (AChE), was found to be heat shock inducible. It is known that MDH and AChE are, respectively, heat shock and 20-hydroxyecdysone inducible (see Introduction). Now it is also known that these enzymes are under dual regulation, with 20-hydroxyecdysone and heat shock being two stimuli which act either separately or in combination, to increase the specific activity of these enzymes. The response to 20-hydroxyecdysone and/or heat shock was found to occur in seven additional D. melanogaster sibling species. In this case, hormone and heat shock maximize the interspecific variability, something which could be acted by natural selection to establish physiological adaptations. |
| Databáze: | OpenAIRE |
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