Further Observations on a Delayed Hypersensitivity Reaction in the Guinea Pig Colon

Autor:	Geron Brown, H. David Hickey, Richard O. Bicks, E.W. Rosenberg
Rok vydání:	1965
Předmět:	Pathology medicine.medical_specialty Necrosis Hepatology Chemistry Gastroenterology Mucous membrane Azathioprine medicine.disease_cause medicine.disease Guinea pig Allergen medicine.anatomical_structure Delayed hypersensitivity Edema medicine medicine.symptom Infiltration (medical) medicine.drug
Zdroj:	Gastroenterology. 48:425-429
ISSN:	0016-5085
DOI:	10.1016/s0016-5085(65)80002-6
Popis:	Summary The severity of a chronic delayed hypersensitivity reaction produced in the guinea pig colon by a constant concentration of 2,4-dinitrochlorobenzene is dependent on the frequency of application of the contactant allergen. The intensity of this reaction can be modified, but not predictably or completely, by azathioprine. The microscopic lesions produced were necrosis of the mucosa, hemorrhagic fibrin deposition, infiltration of small round cells, edema, and perivascular cuffing.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::03be7f48577ed18ab0dc9b67efa82817 https://doi.org/10.1016/s0016-5085(65)80002-6 Zobrazit plný text záznamu