Autor: |
Hamai, Yoko, Fujii, Tomoyuki, Yamashita, Takahiro, Miki, Akinori, Hyodo, Hironobu, Kozuma, Shiro, Geraghty, Daniel E., Taketani, Yuji |
Zdroj: |
American Journal of Reproductive Immunology; February 1999, Vol. 41 Issue: 2 p153-158, 6p |
Abstrakt: |
PROBLEM: We have shown the attenuated human leukocyte antigen (HLA)‐G expression on trophoblasts and an aberrant expression of interleukin (IL)‐2, a cytotoxic cytokine, in decidual tissue in preeclampsia, where deteriorated trophoblastic invasion into decidual layers may constitute a crucial pathogenesis. We hypothesized that the absence of HLA‐G might make trophoblasts susceptible to compromise by IL‐2. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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