| Autor: |
Yuko KAYASUGA-KARIYA, Shintaroh IWANAGA, Ayano FUJISAWA, Lee-Shuan LIN, Shigeki SUZUKI, Ung-il CHUNG, Nobuo SASAKI, Nobuyuki SHIMOHATA, Manabu MOCHIZUKI |
| Předmět: |
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| Zdroj: |
Journal of Veterinary Medical Science; Dec2013, Vol. 75 Issue 12, p1619-1622, 4p |
| Abstrakt: |
The article presents a study based on a hypothesis that the cutaneous irritation caused by topical non-steroidal anti-inflammatory drugs (NSAIDs) could be suppressed by the protective effects of trehalose on biological membranes. Through the Living Skin Equivalent-high human skin model, the effect of the non-reducing disaccharide trehalose was reinforced by co-lyophilization of NSAIDs. It shows how co-lyophilization of NSAIDs with trehalose may be a novel procedure to prevent skin irritation. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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