Autor: |
Veksler IaI, Magomedova KM |
Jazyk: |
ruština |
Zdroj: |
Voprosy meditsinskoi khimii [Vopr Med Khim] 1980 Jul-Aug; Vol. 26 (4), pp. 438-42. |
Abstrakt: |
Resynthesis of aspartate via glutamate was decreased 6-8-fold in rat brain spinal cord tissues due to distinct inhibition of aspartate aminotransferase in acute alcohol intoxication. Consumption of glutamic acid was distinctly increased 1.5-2-fold in tissues of the central nervous system but its metabolism was altered. Normalization occurred within 12-24 hrs after the intake of alcohol. In the state of chronic alcohol intoxication the enzymatic activity was marked increased in brain and spinal cord; in this case the response to a single alcohol administration was altered as compared with acute alcohol intoxication. |
Databáze: |
MEDLINE |
Externí odkaz: |
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