Autor: |
Shurvinton CE, Lloyd RG |
Jazyk: |
angličtina |
Zdroj: |
Molecular & general genetics : MGG [Mol Gen Genet] 1982; Vol. 185 (2), pp. 352-5. |
DOI: |
10.1007/BF00330811 |
Abstrakt: |
Regulation of the ruv gene of E. coli was studied using phage Mud (Ap lac) to obtain a fusion of the lac genes to the ruv promoter. Beta-galactosidase synthesis in the ruv-lac fusion strain was induced by mitomycin C and other agents that damage DNA. The induction of beta-galactosidase could be altered by mutations either in lexA or recA from which it is concluded that ruv is regulated by lexA repressor. A possible function of ruv in promoting cell recovery following damage to DNA is discussed. |
Databáze: |
MEDLINE |
Externí odkaz: |
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