Autor: |
Toghill PJ, Smith PG, Benton P, Brown RC, Matthews HL |
Jazyk: |
angličtina |
Zdroj: |
British medical journal [Br Med J] 1974 Aug 31; Vol. 3 (5930), pp. 545-8. |
DOI: |
10.1136/bmj.3.5930.545 |
Abstrakt: |
Twenty patients are described in whom liver damage appeared to be directly related to the administration of methyldopa. Sixteen had hepatitic syndromes from which they recovered on stopping methyldopa; four of these patients had recurrences of jaundice after a second course of the drug. Features suggestive of active chronic hepatitis were found in two patients. There were two deaths attributed to methyldopa, one of these being in a patient with pre-existing undiagnosed macronodular cirrhosis. |
Databáze: |
MEDLINE |
Externí odkaz: |
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