Autor: |
Volgareva GM, Kil'diushevskaia TV, Del'vig AA, Kozhevnikova EV, Sviridov VV |
Jazyk: |
ruština |
Zdroj: |
Zhurnal mikrobiologii, epidemiologii i immunobiologii [Zh Mikrobiol Epidemiol Immunobiol] 1987 Jan (1), pp. 94-8. |
Abstrakt: |
The tumorigenic capacity of mouse B-cell hybridomas in both cloned and primary cultures was studied. The cells were selected for inoculation from 24-well plates and introduced into the spleen of syngeneic mice. The cells took in 50% of the animals. The cells of hybridoma tumors induced as the result of intrasplenic inoculation, when subcultured in the second passage following the standard scheme, i.e. inoculated intraperitoneally in a dose of 1 X 10(7) cells into mice previously treated with vaseline oil or pristane, produced tumors in 100% of the animals. |
Databáze: |
MEDLINE |
Externí odkaz: |
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