Autor: |
Galassi A, Giovenzana ME, Galbiati E, Auricchio S, Colzani S, Scanziani R |
Jazyk: |
italština |
Zdroj: |
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia [G Ital Nefrol] 2016 Jul-Aug; Vol. 33 (4). |
Abstrakt: |
Phosphate binders represent a common intervention in renal patients affected by chronic kidney disease and mineral bone disorder (CKD-MBD). Although counteracting P overload through binders adoption is argued by a physiology-driven approach, the efficacy of this intervention on hard endpoints remains poorly evident. The inconsistencies between rationale and methodological weakness, concerning the clinical relevance of P binding in chronic kidney disease, will be herein discussed with special focus on the need of a multi-factorial treatment against CKD-MBD, which is currently more achievable due to the variety of P binders and the rapid evolution of nutritional therapy, dialysis techniques and nursing science. |
Databáze: |
MEDLINE |
Externí odkaz: |
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