Cyclodextrin polyrotaxanes as a highly modular platform for the development of imaging agents.

Autor: Fredy JW; Sorbonne Universités, UPMC Univ Paris 06, Institut Parisien de Chimie Moléculaire, UMR 8232, 4 place Jussieu, 75005 Paris (France); CNRS, Institut Parisien de Chimie Moléculaire, UMR 8232, 4 place Jussieu, 75005 Paris (France)., Scelle J, Guenet A, Morel E, de Beaumais SA, Ménand M, Marvaud V, Bonnet CS, Tóth E, Sollogoub M, Vives G, Hasenknopf B
Jazyk: angličtina
Zdroj: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2014 Aug 25; Vol. 20 (35), pp. 10915-20. Date of Electronic Publication: 2014 Jul 28.
DOI: 10.1002/chem.201403635
Abstrakt: Selectively functionalized cyclodextrins with a bodipy fluorescent tag or Gd(3+) complex were synthetized and threaded onto a polyammonium chain to form polyrotaxanes. This modular supramolecular assembly makes an ideal platform for bimodal (fluorescent and MRI) imaging applications.
(© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)
Databáze: MEDLINE
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