Autor: |
Chaves OS; Postgraduate Program in Bioactive Natural and Synthetic Products, Health Sciences Center, Federal University of Paraíba, 58051-970 João Pessoa, PB, Brazil., Gomes RA, Tomaz AC, Fernandes MG, das Graças Mendes L Jr, de Fátima Agra M, Braga VA, de Fátima Vanderlei de Souza M |
Jazyk: |
angličtina |
Zdroj: |
Molecules (Basel, Switzerland) [Molecules] 2013 Mar 01; Vol. 18 (3), pp. 2769-77. Date of Electronic Publication: 2013 Mar 01. |
DOI: |
10.3390/molecules18032769 |
Abstrakt: |
The phytochemical study of Sida rhombifolia L. (Malvaceae) led to the isolation through chromatographic techniques of eleven secondary metabolites: sitosterol (1a) and stigmasterol (1b), sitosterol-3-O-b-D-glucopyranoside (2a) and stigmasterol-3-O-b-D-glucopyranoside (2b), phaeophytin A (3), 17³-ethoxypheophorbide A (4), 13²-hydroxy phaeophytin B (5), 17³-ethoxypheophorbide B (6), 5,7-dihydroxy-4'-methoxyflavone (7), cryptolepinone (8) and a salt of cryptolepine (9). Their structures were identified by ¹H- and ¹³C-NMR using one- and two-dimensional techniques. In addition, the vasorelaxant activity of cryptolepinone in rat mesenteric artery rings is reported herein for the first time. |
Databáze: |
MEDLINE |
Externí odkaz: |
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