Autor: |
Bales KR; Neuroscience Discovery Research, Lilly Research Laboratories Indianapolis, IN 46285, USA., Dodart JC, DeMattos RB, Holtzman DM, Paul SM |
Jazyk: |
angličtina |
Zdroj: |
Molecular interventions [Mol Interv] 2002 Oct; Vol. 2 (6), pp. 363-75, 339. |
DOI: |
10.1124/mi.2.6.363 |
Abstrakt: |
Despite important inroads into the molecular pathology of Alzheimer disease, effective long-term treatment for the condition remains elusive. Among the many gene products that are recognized as factors in the disease is apolipoprotein ( (apoE). The risk that specific isoforms of apoE pose with regard to Alzheimer Disease clearly varies, and so the roles that apoE plays in the brain will be crucial to a full understanding of the disease and to efforts to develop effective therapies. |
Databáze: |
MEDLINE |
Externí odkaz: |
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