[ATP activity of myocardial actomyosin complex in patients with dilated cardiomyopathy].

Autor: Riabenko DV, Sidorik LL, Fedorkova OM, Bobyk VI, Kovenia TV, Tregubov VS, Danilova VM, Matsuka GKh
Jazyk: ruština
Zdroj: Likars'ka sprava [Lik Sprava] 2001 Mar-Apr (2), pp. 36-9.
Abstrakt: ATP activity of actomyosin in dilated cardiomyopathy (DCMP) was studied together with impact on the above activity of tropomyosin-troponin regulatory complexes recovered from the normal myocardium and cardiac muscle of a DCMP patient. Recordable in DCMP was a striking decline (1.5-fold) in ATP activity of actomyosin. But no significant difference was to be seen in sensitivity to Ca2+ ions of actomyosins obtained from the normal myocardium and cardiac muscle of the DCMP patient. The cardial tropomyosin-troponin regulatory complex from the DCMP patient's myocardium was shown to be endowed with somewhat more manifest activity compared to the analogous complex recovered from the normal myocardium.
Databáze: MEDLINE