Barriers in systemic delivery and preclinical testing of synthetic microRNAs in animal models : an experimental study on mir-215-5p mimic /

Mus musculus is the most commonly used animal model in microRNA research; however, little is known about the endogenous miRNome of the animals used in the miRNAtargeting preclinical studies with the human xenografts. In the presented study, we evaluated the NOD/SCID gamma mouse model for the preclin...

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Typ dokumentu: Článek
Jazyk: angličtina
ISSN: 1802-9973
Zdroj: Physiological research: Vol. 70, iss. 3 (2021), s. 481-487.
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