An in vitro study on methotrexate hydroxylation in rat and human liver /
Methotrexate (MTX) was investigated for possible effect on the metabolism of ethoxyresorufin, pentoxyresorufin and ethjxycoumarin, the model substrates of cytochrome P450. The investigation was carried out in liver microsomes of rats pretreated with classical inducers of cytochrome P450 as well as i...
| Hlavní autor: |
Chládek, Jaroslav, 1962-
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Autor )
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| Další autoři: |
Martínková, Jiřina, 1940-
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Autor )
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| Typ dokumentu: | Článek |
| Jazyk: |
angličtina |
| ISSN: | 0862-8408 |
| Zdroj: | Physiological research: Vol. 46, iss. 5 (1997), s. 371-379. |
| Předmět: | |
| Externí odkaz: |
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