A novel carboxymethylated mercaptotriazinoindole inhibitor of aldose reductase interferes with the polyol pathway in streptozotocin-induced diabetic rats /

The aim of the present work was to study the effect of 3- mercapto-5H-1,2,4-triazino[5,6-b]indole-5-acetic acid (CMTI), an efficient aldose reductase inhibitor, on sorbitol accumulation in selected organs of streptozotocin-induced diabetic rats in vivo . In addition, the effect of CMTI on aldose red...

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Další autoři:
Ballekova, J. ( Autor )
Typ dokumentu: Článek
Jazyk: angličtina
ISSN: 0862-8408
Zdroj: Physiological research: Vol. 64, is. 4 (2015), s. 587-591.
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