Transgenic expression of CD36 in the spontaneously hypertensive rat is associated with amelioration of metabolic disturbances but has no effect on hypertension /
Spontaneously hypertensive rats (SHR/NIH strain) harbor a deletion variant in the Cd36 fatty acid transporter and display defective fatty acid metabolism, insulin resistance and hypertension. Transgenic rescue of Cd36 in SHR ameliorates insulin resistance and improves dyslipidemia. However, the role...
Hlavní autor: |
Pravenec, Michal, 1953-
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Autor )
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Další autoři: |
Landa, Vladimír
(
Autor )
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Typ dokumentu: | Článek |
Jazyk: |
angličtina |
ISSN: | 0862-8408 |
Zdroj: | Physiological research: Vol. 52, is. 6 (2003), s. 681-688. |
Předmět: | |
Externí odkaz: |
http://www.biomed.cas.cz/physiolres/2003/issue6.htm |