AMN 082, an agonist of mGluR7, exhibits mixed anti- and proconvulsant effects in developing rats /

Metabotropic glutamate receptors (mGluRs) represent a potential therapeutic target. Possible anticonvulsant action of AMN 082, an agonist of mGluR7 subtype, was studied in immature rats using pentylenetetrazol (PTZ)-induced seizures as a model. Five age groups of rats (7-, 12-, 18-, 25-day-old and a...

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Typ dokumentu: Článek
Jazyk: angličtina
ISSN: 0862-8408
Zdroj: Physiological research: Vol. 57, is. 6 (2008), s. 969-972.
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