Anticonvulsant action of GABA-B receptor agonist SKF97541 differs from that of baclofen /

GABA-B receptor agonist SKF97541 exhibits age-dependent anticonvulsant and proconvulsant actions in developing rats. It suppressed tonic phase of generalized seizures induced by pentetrazol in 7-, 12- and 18-day-old rats and increased their latency in 7- and 12-day-old animals. Other results in 18-d...

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Typ dokumentu: Článek
Jazyk: angličtina
ISSN: 0862-8408
Zdroj: Physiological research: Vol. 57, is. 5 (2008), s. 789-792.
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