Proconvulsant action of two GABAb receptor antagonists is age-dependent /
Antagonists of GABA B receptors are expected to have proconvulsant acti on also in developing brain. Two antagonists (CGP55845 and CGP46381) were tested in a model of cortical epileptic afterdischarges (ADs) in 12-, 18- and 25-day-old rat pups with implanted electrodes. CGP55845 was dissolved in dim...
| Hlavní autor: |
Mareš, Pavel, 1937-
(
Autor )
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|---|---|
| Typ dokumentu: | Článek |
| Jazyk: |
angličtina |
| ISSN: | 0862-8408 |
| Zdroj: | Physiological research: Vol. 62, is. Suppl. 1 (2013), s. S109-S114. |
| Předmět: | |
| Externí odkaz: |
http://www.biomed.cas.cz/physiolres/pdf/62%20Suppl%201/62_S109.pdf
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