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Optic Neuropathy: From Diagnosis to Treatment discusses the pathophysiology, diagnosis, imaging, and treatment of glaucomatous optic neuropathy. A review of optic neuritis, the most common optic neuropathy affecting young adults, is provided. It is a condition involving primary inflammation, demyelination, and axonal injury in the optic nerve which leads to retinal ganglion cell death and visual dysfunction. The authors discuss evidence supporting the idea that monocytes are key players in the initial events that take place during primary optic neuritis. Therefore, strategies aimed at reducing monocyte recruitment into the optic nerve may prove effective against primary optic neuritis-induced visual loss. |
