| Popis: |
The ADP-ribosylation factor (ARF) family of small G-proteins regulates membrane dynamics and intracellular membrane traffic. ARFs are activated upon GTP-binding catalyzed by guanine-nucleotide exchange factors (GEF), which works as a molecular switch and triggers association with specific target membranes. This work focused on the cloning, expression and characterization of genes from the milk yeast K. lactis and the fly D. melanogaster, which are putative homologs of the S. cerevisiae genes GEA1, GEA2, ARF1, ARF2, and ARF3. |
