Softwarové aplikace pokročilých modelů elektromigrace
| Autor: | Malý, Michal |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
capillary zone electrophoresis
vývoj softwaru afinitní kapilární elektroforéza complex-forming equilibria komplexační rovnováhy iontové efektym Onsager-Fuoss Debye-Hückel affinity capillary electrophoresis AnglerFish software development kapilární zónová elektroforéza Debye- Hückel nonlinear theory of electromigration PeakMaster 6 ionic effects nelineární teorie elektromigrace |
| Druh dokumentu: | Doctoral Thesis |
| Popis: | Motion of ions under the influence of electric field has been a subject of scientific interest for many decades. Capillary electrophoresis in particular benefited greatly from this research and mathematical models of electromigration applicable to capillary electrophoresis have been developed. As the sophistication of the models grew, so did the computational demands to evaluate them. In order to fully exploit the possibilities of advanced mathematical models a computer implementation capable of solving non-trivial problems at sufficient speed is necessary. This dissertation thesis explores applications of computer implementations of mathematical models re- lated to electromigration in two different areas. The main focus of this thesis is on the topic of linear theory of electromigration. We discuss the extension of the linear theory of electromigration beyond of just acid-base equilibria and computer implementation of this extented theory which is specialized to include complex-forming equilibria in order to be able to deal with affinity capillary electrophoresis prob- lems. Some technical aspects of the computer implementation are also discussed. This is followed upon by investigating certain selected affinity capillary electrophoresis systems. The purpose of this investi- gation is to re-derive... |
| Databáze: | Networked Digital Library of Theses & Dissertations |
| Externí odkaz: |
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