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Background: Self-Determination Theory (SDT) has been used successfully as a model for health behaviour change in weight loss programs buts its effectiveness promoting physical activity (PA) behaviour change in an elderly population at elevated risk of colon cancer has not been tested. This study investigated the feasibility of implementing an SDT approach in this population and provides preliminary evidence of its efficacy for modifying motivational regulation in the short- and long-term. Furthermore, barriers to participation, and characteristics of non-participators were explored. Trial design: This thesis consists of two randomized controlled feasibility trials. Methods: Trial A was called ‘Physical Activity and Risk of Colon Cancer’ (PARC) and trial B was called ‘MOtiVation for Exercise- promoting an active lifestyle after Colorectal Cancer’ (MOVE). Participants in PARC (n=31, mean age 69y [SD=4.9], BMI 29.3 [SD=5.1]) were patients diagnosed with polyps after a screening colonoscopy. MOVE participants (n=28, mean age 65y [SD=8.3], BMI=27.7 [SD=4.6]) were patients diagnosed with colorectal cancer after completion of treatment. In both studies, participants were randomized to either an active lifestyle programme (ALP) (PARC n=17, MOVE n=14) or the standard care group (SC) (PARC n=14, MOVE n=14). ALP received supervised exercise sessions and physical activity counselling workshops during the intervention and SC was encouraged to continue with their usual lifestyle. For PARC the intervention was 6months with a 6 months follow-up and for MOVE the intervention was 3months with 3 months follow-up. Randomization was carried out with a bespoke computer software (nQuery). The intervention facilitator was not blinded to the group allocation. Data were analysed with intention-to treat analysis. The primary outcomes were the feasibility of the intervention in these populations. Secondary outcomes were variables of behavioural regulation, physical activity behaviour, physical capacity (fitness and strength), self-efficacy, intention to exercise, and quality of life. Results: PARC: Overall recruitment yield was 12.1% of eligible participants. Main barriers for participation for time commitment and distance to research site. Attrition post-intervention was 29% and at follow-up 43%. Attendance at the ii supervised exercise sessions was 62% and at the workshops was 53%. Post-intervention, ALP had lower amotivation (P |
