| Autor: |
Suvarna, S. H. |
| Rok vydání: |
2013 |
| Předmět: |
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| Druh dokumentu: |
Electronic Thesis or Dissertation |
| Popis: |
Objective: A randomized clinical trial seeking evidence as to whether cardioplegic arrest (CA) or intermittent cross-clamp fibrillation (ICCF) method of myocardial protection technique would have any effect on the post-operative neuropsychological outcome in patients undergoing elective coronary artery bypass grafting (CABG) surgery. Methods: One hundred and ninety-five patients were randomized to either CA or ICCF as the method of myocardial protection technique. Cerebral microemboli (ME) during surgery were recorded by transcranial Doppler monitor over the right middle cerebral artery. Evidence of cerebral impairment was obtained by comparing the patients’ performance in a neuropsychological test battery (9 tests) administered 6-8 weeks post-operatively with their pre-operative scores. Results: The groups proved well balanced in pre-operative variables. During cardiopulmonary bypass (CPB) the median number and range of microemboli was 110 (1-1306) in the CA group compared to 105 (9-1757) for the ICCF group (p |
| Databáze: |
Networked Digital Library of Theses & Dissertations |
| Externí odkaz: |
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