Popis: |
The literature reports that phytochemicals from fruits and vegetables, and fruit and vegetable- based products have been associated with decreased risk of cardiovascular disease (CVD). The current research has investigated the effects of fruits and vegetables and blackcurrant juice intake on endothelial function, vascular reactivity and biomarkers of consumption using two human interventions, one acute and one chronic. In addition, gene/nutrient interactions have been investigated with three genotypes linked to markers of CVD in the chronic study. / The acute study was a randomised, cross over, double blind, placebo controlled test meal study with 20 healthy volunteers (11 females 9 males). Subjects consumed a 20% blackcurrant juice drink or a control drink. Vascular reactivity was assessed at baseline and 120 mins after juice consumption by Laser Doppler Imaging (LDI). Acute consumption of 20% blackcurrant juice significantly increased plasma vitamin C (P=0.006), and urinary anthocyanins (P |