On the role of TRPA1 in acute and inflammatory nociception

Autor: Dunham, James Philip
Rok vydání: 2008
Předmět:
Druh dokumentu: Electronic Thesis or Dissertation
Popis: Injury is detected by a population of sensory nerves called nociceptors. Nociceptor sensitisation enhances pain and serves as a protective mechanism which promotes recovery. However, pain can become chronic. When this occurs pain becomes pathological in its own right and has extremely deleterious effects on the patient. A fuller understanding of the mechanisms by which nociceptors become sensitised and detect physiological stimuli is required to better treat chronic pain.
Databáze: Networked Digital Library of Theses & Dissertations