| Autor: |
Stephens, Deborah M, Li, Hongli, LeBlanc, Michael L, Puvvada, Soham D, Persky, Daniel, Friedberg, Jonathan W, Smith, Sonali M |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Druh dokumentu: |
Článek |
| ISSN: |
1527-7755 |
| DOI: |
10.1200/JCO.2015.65.4582 |
| Popis: |
Utility of combined-modality therapy for patients with limited-stage diffuse large B-cell lymphoma (DLBCL) was shown in the Southwest Oncology Group (SWOG) S8736 study, where three cycles of CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) plus radiotherapy (CHOP3RT) improved 5-year progression-free (PFS) and overall survival (OS) compared with eight cycles of CHOP (CHOP8). Subsequent analysis showed an unexpected overlap of the PFS curves. We aimed to confirm and investigate this observation by performing long-term analysis of SWOG S8736 and evaluating these data alongside data from similar patients receiving rituximab and CHOP3RT (SWOG S0014 study). |
| Databáze: |
Networked Digital Library of Theses & Dissertations |
| Externí odkaz: |
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