| Autor: |
Schissler, A Grant, Li, Qike, Chen, James L, Kenost, Colleen, Achour, Ikbel, Billheimer, D Dean, Li, Haiquan, Piegorsch, Walter W, Lussier, Yves A |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Druh dokumentu: |
Článek |
| ISSN: |
1367-4811 |
| DOI: |
10.1093/bioinformatics/btw248 |
| Popis: |
As 'omics' biotechnologies accelerate the capability to contrast a myriad of molecular measurements from a single cell, they also exacerbate current analytical limitations for detecting meaningful single-cell dysregulations. Moreover, mRNA expression alone lacks functional interpretation, limiting opportunities for translation of single-cell transcriptomic insights to precision medicine. Lastly, most single-cell RNA-sequencing analytic approaches are not designed to investigate small populations of cells such as circulating tumor cells shed from solid tumors and isolated from patient blood samples. |
| Databáze: |
Networked Digital Library of Theses & Dissertations |
| Externí odkaz: |
|
