Change of Sleep Disturbance and Its Relationship with Symptoms Severity and Post-Traumatic Stress Symptoms in Head and Neck Cancer Patients During and Post-Concurrent Chemoradiotherapy

Autor: Yu-Chieh Su, 蘇郁捷
Rok vydání: 2018
Druh dokumentu: 學位論文 ; thesis
Popis: 107
Background: Head and neck (HNC) cancer patients experience symptoms severity and post-traumatic stress symptoms (PTSS), which might influence sleep disturbance. However, limited research has explored how they affect sleep disturbance simultaneously. Aim: (1)Explore changes of symptoms severity, post-traumatic stress symptoms and sleep disturbance. (2)The relationship in symptoms severity, post-traumatic stress symptoms and sleep disturbance in HNC patients. Study design: A longitudinal prospective study was designed to collect data since pre-concurrent chemoradiotherapy (CCRT) to receiving CCRT for three month. The questionnaires we used were Symptom Severity Scale, Impact Event Scale-Revised, and Medical Outcome Study- Sleep Scale. The Generalized Estimating Equations was used to analyze the factors that influence change in sleep disturbance. Result: Sixty eligible subjects completed this survey. The results indicated: (1) no significant difference in disease characteristics and sleep disturbance. (2) The overall symptoms severity, post-traumatic stress symptoms and sleep disturbance reached a peak in the second month of radiotherapy and then decreased significantly in the third month of treatment, but still higher than before radiotherapy. (3) Performance status (KPS), Fatigue, dry mouth, oral mucositis, and post-traumatic stress symptoms significantly correlated with sleep disturbance. Conclusion: Medical professionals should understand sleep problems in HNC patients, and pay more attention to evaluate factors that interfere with sleep disturbances, including symptoms severity and the impact of cancer, during and post treatment. With appropriate symptom control, and help patients to cope with the changes in daily life.
Databáze: Networked Digital Library of Theses & Dissertations
Externí odkaz: