Beam Angle Optimization with Patient-Specific Collision Detection for External Beam Radiation Therapy
| Autor: | Jia-Sheng Yao, 姚嘉昇 |
|---|---|
| Rok vydání: | 2019 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 107 Beam angle optimization is a critical issue for modern RT, and this could be challenging under non-coplanar settings. Non-coplanar radiation therapy techniques have potential dosimetry advantages but with the increase in the risk of collision. Collision detection is important in external beam radiation therapy to help eliminate the needed time to confirm the usability of selected beam angles and prevent patient machine collisions. Our goal is to establish a platform which is patient-specific to calculate the collision space before treatment planning, prevent hardware damage, and improve patient safety to help physicians choose the safe and applicable beam angles wisely for enhancing dosimetric distributions. Two different models were built and validated. Compared with our application prediction, the collision angles were predicted within the different range of 7 degrees. The confusion matrix was applied for two different linear accelerators models, and the accuracy was 0.989 (0.989 and 0.973 respectively). True positive rate (TPR) and true negative rate (TNR) were 0.978 (0.978 and 0.969) and 0.998 (0.998 and 0.980) respectively. Our application is a simple, effective, and convenient tool to simulate the collision detection without the extra equipment and further help radiation therapy treatment planning smarty for the beam angle optimization. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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