Parametric likelihood inference with censored survival data under the COM-Poisson cure models

Autor: Zhisheng He, 何致晟
Rok vydání: 2017
Druh dokumentu: 學位論文 ; thesis
Popis: 105
Rodrigues et al. (2009) proposed the Conway-Maxwell-Poisson (COM-Poisson) distribution as a model for a cure rate in censored survival data. We consider computational algorithms for maximum likelihood estimation under the Bernoulli cure rate model, a special case of the COM-Poisson cure rate model. The Weibull distribution (Balakrishnan and Pal 2016) and the generalized gamma distribution (Balakrishnan and Pal 2015) are considered as lifetime distributions. We obtain all the expressions of the score function and Hessian matrix to perform the Newton-Raphson and EM algorithms. Simulations are conducted to compare the performance between the EM algorithm and Newton-Raphson algorithms. Finally, a real data is analyzed to illustrate the methods.
Databáze: Networked Digital Library of Theses & Dissertations