Studies on the Development of the Asymmetric Synthesis of Various Sphinganines:Synthesis of Sphinganine with Eighteen Carbons
| Autor: | Yu-Lin Ho, 賀有鄰 |
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| Rok vydání: | 2017 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 105 The use of D-xylose as a starting material, the use of asymmetric synthesis of palm pond method, the rapid establishment of the required three-dimensional position of the main structure of the compound, and then use Wittig reagent to establish terminal double bond, and the introduction of Grubbs II reagent The desired long carbon chain, and finally the SN2 reaction to establish the backward position of the amine, and then hydrogenation to remove all the protective groups, through 15 steps to get the target product of sphingosine alcohol. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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