A new scheme to identify microbial toxicity based on Next-Generation Sequencing and metatranscriptomics
| Autor: | Wei-Sheng Chuang, 莊為勝 |
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| Rok vydání: | 2016 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 104 Various microbes exist in our surroundings, including bacteria, virus and archaea. Different environments have different kinds of microbe communities. Based on this, different microbial genomes play important roles in different parts of human bodies. This study focuses on bacteria and their toxicity in the human intestines and try to find out whether different diets will have direct influences on bacteria in the intestines and the changes in toxin contents. Based on the functional genomics of the bacteria, we will have an overall understanding of the bacteria in the intestines and toxin environment. In this research, we constructed the microbial toxicity identification system. The relationship between microbial communities and the natural environment could be explored by a further investigation of microbial toxicity. The comprehensive and optimized analysis platform will be constructed and verified through this proposal and this platform can be applied to many fields such as food, environment and human health testing. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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