Implicit attitude and inhibitory control ability in betel quid chewers

Autor: Yu-Kwan Tong, 唐愉君
Rok vydání: 2016
Druh dokumentu: 學位論文 ; thesis
Popis: 104
Although betel nut is a harmful carcinogen and lead to dependence, betel nut chewing is still very common. There are about 1.95 million adults chewing betel in Taiwan. In this study, we aimed to examine whether chewing betel quid affect inhibitory control ability and whether high betel quid dependent chewer have a positive implicit attitude toward betel. Three groups of participants (high dependence, cigarette/alcohol user, and healthy control) were asked to complete two cognitive tasks (Stop signal task and Single category implicit association test) that assess motor inhibitory control and implicit attitude toward betel, and Magnetic Resonance Imaging (MRI). The results found that, the main effect of stop signal reaction time (SSRT) and D score were both not significant difference between three groups, but omission rate was significant difference between high dependence and healthy group. In Resting state MRI, SSRT was significantly correlated with left middle occipital gyrus, precentral gyrus, left superior temporal gyrus, right precuneus, cuneus and right caudate nucleus; D score was significantly correlated with left precuneus and left thalamus. In diffusion MRI, SSRT was significantly correlated with insula, cerebral peduncle, corticospinal tract, left superior parietal gyrus, left inferior parietal gyrus, left middle occipital gyrus, left postcentral gyrus, and superior frontal gyrus; D score was significantly correlated with insula, right angular gyrus, and left precuneus. This research provides some information toward increasing understanding of betel quid user.
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