Study on Nanosecond Pulse Laser and Nanowire Processing of Electric Impedance Sensors for Biomedical Detection
| Autor: | Chang, Chieh-Fu, 張傑富 |
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| Rok vydání: | 2015 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 103 With the progress of nanotechnology, there are a great amount of researches about fabricating sensors by means of nano processes techniques in recent years, especially for biomedical sensing devices. Compared with the testing machine in the hospital, biochips can achieve point of care. The disease can be analyzed instantaneously for patient that can be helpful to the goal of preventive medicine. Our research is to use the nanosecond laser micromachining techniques for fabricating the screen-printed multilayered graphene electrodes. The experimental conditions based on the laser fluence and pulsed overlap can affect the width and depth of multilayered graphene. This study uses the nanosecond laser pulses with the ultraviolet (UV) wavelength that can fabricate the minimum electrode distance of 60 μm. Combined with the electrospinning technique, the nanofiber membrane which is made by polyvinyl alcohol (PVA) and glucose oxidase is fabricated on the surface of electrodes. The resistance response is measured through the different concentration of glucose. It can be found that there is the obvious change for the electrical resistance when the glucose concentration is 0.011 mM. In addition, the current response approaches a linear behavior when the glucose concentration is ranging between 0.011 mM and 0.41 mM. It can demonstrate that a prospective value for detection of the lower glucose concentration. Therefore, the study will be a possible opportunity for applying in manufacturing biochip and mass production. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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