Rapid Viral Response and Comparison with Very-Rapid Viral Response in Chronic Hepatitis C virus Genotype 1

Autor: Yu-Lin Tan, 談兪麟
Rok vydání: 2014
Druh dokumentu: 學位論文 ; thesis
Popis: 102
Background: Hepatitis C virus was discovered in 1989, and its infection may cause chronic hepatitis C cirrhosis, liver cancer and some patients would need liver transplantation. The total number of these patients in the world is around 170 million per year. Purpose: Research Patients’ characteristics, to find a higher probability of treatment success while reducing the side effects and reducing medial cost. Methods: Collected 183 patients with chronic hepatitis C, analysis of the collected patients by 16 patient characteristics including very rapid viral response prediction. Result: 99% of patients who has very-rapid viral response at second week of treatment will have sustained virological response at one year even only received treatment for 6 months. Conclusion: Very-Rapid viral response is a more powerful prediction about the need of treatment duration than rapid viral response. Key words:Chronic Hepatitis C Virus, Rapid Viral Response, Very-Rapid Viral Response, sustained virological response.
Databáze: Networked Digital Library of Theses & Dissertations