Cardiovascular risk factors of internal carotid artery stenosis in type II diabetes
| Autor: | Hsiao-Ching Lin, 林曉菁 |
|---|---|
| Rok vydání: | 2014 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 102 Background Carotid artery stenosis is an important cause of cerebral ischemia for patients with type II diabetes mellitus (DM). Carotid artery stenosis might induce ischemic stroke. It have been recognized as an useful tool to assess the risk of cerebrovascular diseases. Therefore, identifying the potential of developing cerebral infarction is clinically important for DM patients. Objective Present study investigated the cardiovascular related risk factors in type II DM. Methods This cross sectional study recruited 83 patients with type II DM. There were 53 men and 30 women. Their mean age was 66.2 ± 6.3 years. All patients underwent extracranial color-coded duplex sonography. We measured their lipid profile, coagulation, fibrinolytic and inflammation parameters. Cardiovascular risk factors including hypertension, diabetes mellitus, dyslipidemia, obesity, smoking, alcohol and physical activity were evaluated. Test statistics included the chi-spuare test, independent t test, and multiple logistic regression. Results 28.9% (n=24) of patients had internal carotid artery stenosis. Lipoprotein(a) (OR= 3.147, 95% CI:1.134-8.739, P=0.028) and high-sensitivity C-reactive protein (OR= 2.511, 95% CI:1.022-6.168, P=0.045) were the independent predictor for internal carotid artery stenosis. Conclusions Elevated Lp(a) and hs-CRP increased the risk of internal carotid artery stenosis in type II DM subjects. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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