Evaluation of the Bioactivities of Aqueous Extract From Seven Herbal Plants
| Autor: | Che Chang Yang, 楊哲彰 |
|---|---|
| Rok vydání: | 2013 |
| Druh dokumentu: | 學位論文 ; thesis |
| Popis: | 101 Medicinal herbs have used for a very long time in human’s history, but lack of the significant evidence and data in science. In the present investigation, we evaluated whether those seven herbal aqueous extracts contained the antibacterial, antioxidative and anti-inflammatory capacity at the same time. Our results showed that Lagerstroemia indica L. exhibited a good antibacterial activity against B. subtilis and two Gram-negative bacteria (E. coli, P. aeruginosa) with the inhibitory zone of 14-19 mm. Lagerstroemia indica L. and Evodia Lepta(Spreng.)Meer. displayed the lowest value of EC50 (16.09±0.85 and 29.14±1.91 μg/mL) to scavenge the DPPH radicals. The total flavonoid content of Euonymus laxiflorus Champ. and Evodia Lepta(Spreng.)Meer. were equal to 158.40±2.26 and 155.60±3.59 mg CE/g extract, respectively. The total phenolic content of Evodia Lepta(Spreng.)Meer. and Duranta repens L. were up to 293.70±16.4 and 212.90±5.14 mg GAE/g extract, respectively. For the reducing power assay, the lowest EC50 value was shown in Lagerstroemia indica L. (10.92±0.45 μg/mL) and Evodia Lepta(Spreng.)Meer. (19.75±0.97 μg/mL). The TEAC value of Lagerstroemia indica L. and Evodia Lepta(Spreng.)Meer. were equal to 2.64±0.17 and 2.46±0.50 mmol TE/g extract, respectively. For the ferrous ion-chelating ability, the lowest EC50 value was exhibited by Lagerstroemia indica L. (1.250±0.10 mg/mL) and Alpina katsumadai Hayata (1.610±0.05 mg/mL). The best value of inhibiting lipid peroxidation were 85.02±4.61% and 83.91±1.73% in 100 μg/mL of Bauhinia variegata L. and Alpina katsumadai Hayata aqueous extract. For the anti-inflammation test, Lagerstroemia indica L., Alpina katsumadai Hayata and Euonymus laxiflorus Champ. could decrease the hyaluronidase activity. For the cell viability assay, all the samples showed no cytotoxicity below 200 μg/mL. Therefore, the multiple functions of Lagerstroemia indica L. will be applied in the clinical, medical, cosmetic and biotechnological fields. |
| Databáze: | Networked Digital Library of Theses & Dissertations |
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