Screening mammography efficacy: a comparison between screen-film, computed radiography and digital mammography

Autor: Chia-Hsing Lin, 林家興
Rok vydání: 2011
Druh dokumentu: 學位論文 ; thesis
Popis: 100
Purpose: Breast cancer screening has been proven effective in Western countries. Taiwan National Health Bureau started to offer free screening mammography for women aged between 50 and 69 since July 2004. This study aims to compare the efficacy between different modalities of screening mammography. Material and Methods: Between July 2004 and December 2010, a total of 23513 eligible women underwent screening mammography in our hospital. 6804 of these received screen-film mammography, 1610 received computed-radiography mammography, and 15099 received digital mammography. The carcinoma-in-situ detection rate, early cancer detection rate, and the overall cancer detection rate of each modality were calculated. Chi-square test was used to determine the statistical significance of performance differences between these modalities. Results: The callback rate of screen-film mammography (SFM) was 12.23%, cancer detection rate was 5.29%, DCIS detection rate was 1.76%. The callback rate of computed radiography (CR) was 12.67%, cancer detection rate was 6.21% and DCIS detection rate was 1.24%. Full-field digital mammography (FFDM) has the highest callback rate of 9.21%, but also the highest rate of cancer detection rate and DCIS detection rate of 9.21% and 3.58% respectively. FFDM has better cancer detection rate and DCIS detection rate compared to SFM and CR, it is only statistically significant when compared to SFM. Although FFDM has better cancer and DCIS detection rates, it is also associated with higher callback rate. Conclusions: Full-field digital mammography has obvious performance advantages over screen-film and computed radiography mammography, this is important especially in Asian populations where dense breasts are more prevalent. Taiwanese breast cancer incidence is gradually increasing and becoming comparable to that of Western countries, and when combined with dense breasts of Asian women and Taiwan’s unique medicolegal ecosystem, results in relatively high callback rate.
Databáze: Networked Digital Library of Theses & Dissertations
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