Control hydrogel photopolymerization inside live systems by X-ray irradiation for biomedical application

Autor: Yi-Da Kang, 康宜達
Rok vydání: 2012
Druh dokumentu: 學位論文 ; thesis
Popis: 100
We successfully demonstrate the in situ formation by X-ray irradiation induced polymerization of a three-dimensional (3D) hydrogel based on poly(ethylene glycol) (PEG) diacrylate (PEG DA), with the option of heparin incorporation to enhance cell adhesion. The polymerization reaction can be completed in tens of seconds, thanks to the fast and uniform X-ray induced process. Through the incorporation of Au NPs and fast-crosslink biomaterials, we are not only reduce the damage to surrounding tissues but also raise the gelling efficiency.
Databáze: Networked Digital Library of Theses & Dissertations